Publications

Gover, G.J., Kelly, J., Moore, G., Jacoby, H., Karmali, R.A., Gorman, G.S. Comparative Pharmacokinetic profile of carboxyamidotriazole and carboxyamidotriazole orotate. Cancer Therapy, 2007, 5: 437-442.

Karmali R., Maxuitenko, Y., Gorman, G., Page, J.G. Carboxyamidotriazole Orotate and Cytotoxic Chemotherapy have a synergistic Effect on Tumor Inhibition in Glioblastoma and Colon Xenograft Mouse Models. Cancer Therapy. 2011;8:71-80. Epub 20 December 2011.

Corrado, C., Flugy, A.M., Taverna, S., Raimondo, S., Guggino, G., Karmali, R.A., et al. (2012) Carboxyamidotriazoleorotate Inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis. PLoS One, 7(8).

Karmali, R.A., Maxuitenko, Y., Gorman, G., Qu, Z. Combinatorial treatment with Carmoxyamidotriazole Orotate and Temozolomide in sc-Implanted human LOX IMVI melanoma xenografts. J. Solid Tumors, 2012, 2: 1-16.

Karmali, R.A., Maxuitenko, Y., Gorman, G. Treatment with Paclitaxel Orotate and Carboxyamidotriazole Orotate in SC-Implanted OVCAR-5 Human Ovarian Tumor Xenografts. J. Cancer Therapy, 2013, 4: 857-871.

Taylor M.H., Sandler A., Urba W.J., Omuro A.M.P., Gorman G.S., Karmali R.A.. Effect of carboxyamidotriazole orotate, a modulator or calcium-dependent signaling pathways, on advanced solid tumors. JCT. 2015; 6:322-333.